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Split Prime Editing Platforms

Development of Split Prime Editing Platforms [1]

Dr. Pablo Perez-Pinera has developed a method to divide prime editing tools into smaller components that are small enough to be delivered in adeno-associated viruses, an FDA-approved vehicle for therapeutic use. Prime editors have recently shown great promise as gene editing tools with greater specificity and fewer off-target effects than existing CRISPR-Cas based methods. This technology has potential as a research tool as well as a therapeutic strategy.
 

Pablo
Perez-Pinera

Inventors:

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[1] https://origin.otm.illinois.edu/technologies/development-split-prime-editing-platforms